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INHIBITION OF LEUKOTRIENE SYNTHESIS AND ACTIVITY IN THE TREATMENT OF SONIC HEDGEHOG-ASSOCIATED MEDULLOBLASTOMA
INHIBITION OF LEUKOTRIENE SYNTHESIS AND ACTIVITY IN THE TREATMENT OF SONIC HEDGEHOG-ASSOCIATED MEDULLOBLASTOMA
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机译:抑制白三烯的合成及其在治疗声波刺猬相关的髓母细胞增生中的活性
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Treating Sonic Hedgehog-Associated Medulloblastoma comprises inhibiting the synthesis or biologic activity of leukotrienes that drive Nestin expression in cancerous or precancerous granule neuron precursors and that further drive growth and proliferation of medulloblastoma cells through Nestin-mediated aberrant Sonic Hedgehog signaling.
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