首页> 外国专利> METHOD FOR INHIBITING CELL PROLIFERATION BY OXIDATIVE STRESS

METHOD FOR INHIBITING CELL PROLIFERATION BY OXIDATIVE STRESS

机译:氧化应激抑制细胞增殖的方法

摘要

The present invention relates to an intracellular oxidative stress promoter, comprising a monoclonal antibody having an inhibitory activity of intracellular uptake of neutral amino acids or an antibody fragment thereof as an active ingredient. Also, the present invention relates to a cell proliferation inhibitor, comprising a monoclonal antibody having an inhibitory activity of intracellular uptake of neutral amino acids or an antibody fragment thereof as an active ingredient and promoting intracellular oxidative stress.;Further, the present invention relates to a method for promoting intracellular oxidative stress, comprising administration of a monoclonal antibody having an inhibitory activity of intracellular uptake of neutral amino acids or an antibody fragment thereof. Also, the present invention relates to a method for inhibiting cell proliferation, comprising administration of a monoclonal antibody having an inhibitory activity of intracellular uptake of neutral amino acids or an antibody fragment thereof and promotion of intracellular oxidative stress.
机译:本发明涉及一种细胞内氧化应激促进剂,其包含具有抑制细胞内摄取中性氨基酸的活性的单克隆抗体或其抗体片段作为有效成分。另外,本发明涉及细胞增殖抑制剂,其包含具有抑制细胞内摄取中性氨基酸的活性的单克隆抗体或其抗体片段作为有效成分并促进细胞内氧化应激。一种促进细胞内氧化应激的方法,包括给予具有抑制细胞内摄取中性氨基酸的活性的单克隆抗体或其抗体片段。另外,本发明涉及抑制细胞增殖的方法,其包括给予具有抑制细胞内摄取中性氨基酸或其抗体片段的活性并促进细胞内氧化应激的单克隆抗体。

著录项

  • 公开/公告号US2014134730A1

    专利类型

  • 公开/公告日2014-05-15

    原文格式PDF

  • 申请/专利权人 KYOWA HAKKO KIRIN CO. LTD;

    申请/专利号US201314062009

  • 发明设计人 AYA SASAKAWA;YOSHIKI SUMITOMO;

    申请日2013-10-24

  • 分类号C07K16/30;

  • 国家 US

  • 入库时间 2022-08-21 16:09:28

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