QUANTITATIVE MODELS OF MULTI-ALLELIC MULTI-LOCI INTERACTIONS

摘要

Various embodiments generate a quantitative model of multi-allelic multi-loci interactions. In one embodiment, a plurality of distinct allelic forms of at least two loci of an entity is received. Each of the plurality of distinct allelic forms is associated with a set of genotypes. A contribution value of each genotype to a given physical trait is determined for each set of genotypes. An interaction contribution value for each interaction between each of the set of genotypes of a first of the least two loci and each of the set of genotypes of at least a second of the least two loci to the physical trait is determined from at least one interaction model. A model of a quantitative value of the entity is generated based on the contribution value of each genotype in each set of genotypes and each interaction contribution value that has been determined from the interaction model.