The present invention discloses a preparation method for extractive of Jinxuan Hemorrhoid Washing Powder botanicals comprises the steps: A, honeysuckle, schizonepeta, and purslane in the prescription of Jinxuan Hemorrhoid Washing Powder are mixed, ground, and passed through a mesh; the medicinal powder obtained from supercritical extraction is soaked in alcohol, then undergoes percolation extraction, and the percolate is collected; B, the alcohol percolate is concentrated, left stand, and suction filtrated to obtain a filtrate; C, the filtrate macroporously adsorpts to a resin column at a flow velocity, is then removed of to impurity by water washing, and undergoes elution with alcohol to obtain an alcohol eluent; D, alcohol is recovered from the eluent, the remaining liquid is concentrated, and the concentrated liquid is dried to obtain the extractive of Jinxuan Hemorrhoid Washing Powder botanicals. The method is simple and produces high active substance content at a lower production cost and energy consumption. The total content of flavones, saponins, and organic acids exceeds 70%. The extractive has substantial anti-inflammatory and pain relieving effects.
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