AUTOMATED HIGH-CONTENT IMAGE ANALYSIS SYSTEM AND METHODS AND USES THEREOF

摘要

This invention relates to algorithms, methods and products useful in assessing steatosis level of tissues, using an automated high-content image analysis framework. The algorithms, methods and products are particularly useful in liver transplantation by providing a fast, precise and reproducible steatosis level estimation pre-transplantation. The invention also enables in vitro high throughput screening of drug candidates for reducing intra-cellular triglyceride content in the form of lipid droplets from fatty livers.