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Method and System for Knowledge Pattern Search and Analysis for Selecting Microorganisms Based on Desired Metabolic Property or Biological Behavior

机译:基于所需代谢特性或生物学行为的微生物知识模式搜索与选择方法及系统

摘要

Methods and systems for knowledge pattern search and analysis for selecting microorganisms based on desired metabolic properties or biological behaviors are disclosed in various embodiments of the invention. In one embodiment of the invention, a computer-implemented method for selecting a purpose-specific microorganism first compiles microorganisms' profiles by linking each microorganism's methanogenic, hydrogenic, electrogenic, another metabolic property, and/or another biological behavior to genetic and chemical fingerprints of metabolic and energy-generating biological pathways. Then, based on the compiled profiles of the microorganisms, the computer-implemented method groups the microorganisms into pathway characteristics using machine-learning and pattern recognition performed on a computer system, and subsequently generates a prediction called “discovered characteristics” for a desired metabolic property or a desired biological behavior of at least one microorganism. Furthermore, a profile match score may be calculated to indicate usefulness of one or more microorganisms for renewable energy generation from biological waste materials or wastewater.
机译:在本发明的各种实施方式中公开了用于知识模式搜索和分析以基于期望的代谢特性或生物学行为选择微生物的方法和系统。在本发明的一个实施方案中,一种用于选择特定目的微生物的计算机实现的方法首先通过将每种微生物的产甲烷,产氢,产电,另一种代谢特性和/或另一种生物学行为与微生物的遗传和化学指纹联系起来来汇编微生物的概况。代谢和产生能量的生物途径。然后,基于编译后的微生物特征,计算机执行的方法使用在计算机系统上进行的机器学习和模式识别将微生物分组为途径特征,然后针对所需的代谢特性生成称为“发现的特征”的预测或至少一种微生物的期望生物学行为。此外,可以计算轮廓匹配分数以指示一种或多种微生物对从生物废料或废水产生可再生能源的有用性。

著录项

  • 公开/公告号US2014088883A1

    专利类型

  • 公开/公告日2014-03-27

    原文格式PDF

  • 申请/专利权人 CHARLES C. ZHOU;YING ZHAO;

    申请/专利号US201314093520

  • 发明设计人 CHARLES C. ZHOU;YING ZHAO;

    申请日2013-12-02

  • 分类号G06F19/24;

  • 国家 US

  • 入库时间 2022-08-21 16:06:31

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