ANALYSIS OF THE METHYLATION PATTERN OF THE ALPHA-SYNUCLEIN GENE FROM DNA OF PERIPHERAL BLOOD MONOCYTES FOR DIAGNOSING PARKINSON'S DISEASE

摘要

A method of using peripheral blood monocytes of a patient to at least one of diagnose and assess a risk of a patient of developing Parkinson's disease includes obtaining peripheral blood monocytes from the patient, and determining a methylation pattern of the SNCA_{(−926/−483)} region of the SNCA gene of the DNA of the peripheral blood monocytes.