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PIG MYOSTATIN GENE LOCUS AND USES THEREOF

机译:猪肌生成抑制素基因位点及其用途

摘要

A pig myostatin gene locus and uses thereof are provided. Also provided includes an expression cassette comprising a promoter, a foreign gene and a following terminator; the promoter is a DNA molecule as set forth in any of 1)-4): 1) nucleotides at positions 2642-3778 starting from the 5′ end of SEQ ID NO. 1 in the sequence listing; 2) nucleotides as set forth in SEQ ID NO. 1 in the sequence listing; 3) a DNA molecule, hybridizing and having the same function with the DNA sequence as defined in 1) or 2) under stringent condition. Experiments show that the pig myostatin gene locus provides a valuable gene source for gene targeting, as well as introducing and expressing a foreign gene at this site.
机译:提供了猪肌生长抑制素基因位点及其用途。还提供了包括启动子,外源基因和随后的终止子的表达盒;该启动子是如1)-4)中任一项所述的DNA分子:1)从SEQ ID NO.5的5'端开始的2642-3778位的核苷酸。序列表中的1; 2)如SEQ ID NO.1所示的核苷酸。序列表中的1; 3)在严格条件下与1)或2)中定义的DNA序列杂交并具有相同功能的DNA分子。实验表明,猪肌肉生长抑制素基因位点为靶向基因以及在该位点引入和表达外源基因提供了宝贵的基因来源。

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