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LYOPHILIZED LIPOSOME COMPOSITION ENCAPSULATING A WATER-SOLUBLE DRUG AND PREPARATION PROCESS THEREOF
LYOPHILIZED LIPOSOME COMPOSITION ENCAPSULATING A WATER-SOLUBLE DRUG AND PREPARATION PROCESS THEREOF
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机译:囊化水溶性药物的脂质体脂质体组合物及其制备方法
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摘要
Disclosed is a lyophilized liposome composition encapsulating a water-soluble drug and a preparation process thereof. The lyophilized liposome composition comprises a water-soluble drug, a phospholipid, a polyethylene glycol-derivatized phospholipid, cholesterol and a lyoprotectant, wherein the lyoprotectant comprises a saccharide and a cyclodextrin or cyclodextrin derivative. The encapsulation rate of the lyophilized liposome composition encapsulating the water-soluble drug is ≧90%.
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