首页> 外国专利> PHARMACEUTICAL COMPOSITION COMPRISING ANTIBODIES AGAINST CATALASE AND SUPEROXIDE DISMUTASE FOR TUMOR THERAPY

PHARMACEUTICAL COMPOSITION COMPRISING ANTIBODIES AGAINST CATALASE AND SUPEROXIDE DISMUTASE FOR TUMOR THERAPY

机译:含抗过氧化氢酶和过氧化物歧化酶抗体的药物组合物,用于肿瘤治疗

摘要

The present invention is based on the unexpected finding that, in addition to catalase, SOD is also involved in protecting tumor cells, wherein the inhibition effects of the two protective enzymes support one another in a complementary manner. The invention thus relates to pharmaceutical compositions containing at least two antibodies or the biologically active fragments thereof, wherein the one antibody is directed against the catalase and the other antibody is directed against the superoxide dismutase, as well as their use for treating a tumor disease.
机译:本发明基于出乎意料的发现,即除了过氧化氢酶外,SOD还参与保护肿瘤细胞,其中两种保护酶的抑制作用以互补的方式相互支持。因此,本发明涉及包含至少两种抗体或其生物活性片段的药物组合物,其中一种抗体针对过氧化氢酶,另一种抗体针对超氧化物歧化酶,及其用于治疗肿瘤疾病的用途。

著录项

  • 公开/公告号US2014099327A1

    专利类型

  • 公开/公告日2014-04-10

    原文格式PDF

  • 申请/专利权人 GEORG BAUER;

    申请/专利号US201214119177

  • 发明设计人 GEORG BAUER;

    申请日2012-06-15

  • 分类号A61K39/395;

  • 国家 US

  • 入库时间 2022-08-21 16:04:26

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