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Isolation of anti-desmoglein 1 antibodies by phage display of pemphigus foliaceus autoantibodies
Isolation of anti-desmoglein 1 antibodies by phage display of pemphigus foliaceus autoantibodies
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机译:通过噬菌斑叶天疱疮自身抗体的噬菌体展示分离抗桥粒芯蛋白1抗体
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摘要
This invention relates to compositions and methods for the use of anti-autoimmune reagents that specifically bind to anti-desmoglein antibodies, which are responsible for pemphigus foliaceus. In addition, the invention relates to methods and compositions for inhibiting the expression or function of a variable region of an anti-desmoglein (anti-Dsg) pathogenic autoantibody.
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