首页> 外国专利> Progesterone antagonists such as CDB-4124 in the treatment of endometriosis, uterine fibroids, dysmenorrhea, breast cancer, etc

Progesterone antagonists such as CDB-4124 in the treatment of endometriosis, uterine fibroids, dysmenorrhea, breast cancer, etc

机译:孕酮拮抗剂,例如CDB-4124,用于治疗子宫内膜异位症,子宫肌瘤,痛经,乳腺癌等

摘要

The present invention relates to methods of administering compositions comprising a progesterone receptor antagonist for use in treating estrogen-dependent conditions. The invention is also directed to methods for treating pain associated with endometriosis. The compositions may be administered to females with endometriosis as well as to females undergoing estrogen and/or selective estrogen receptor modulator (SERM) therapy. In certain embodiments, the invention provides a method for suppressing endometrial proliferation.
机译:本发明涉及用于治疗雌激素依赖性疾病的包含孕酮受体拮抗剂的组合物的给药方法。本发明还涉及用于治疗与子宫内膜异位相关的疼痛的方法。可以将组合物给予患有子宫内膜异位的女性以及接受雌激素和/或选择性雌激素受体调节剂(SERM)治疗的女性。在某些实施方案中,本发明提供了抑制子宫内膜增生的方法。

著录项

  • 公开/公告号US8735381B2

    专利类型

  • 公开/公告日2014-05-27

    原文格式PDF

  • 申请/专利权人 REPROS THERAPEUTICS INC.;

    申请/专利号US201313855559

  • 发明设计人 JOSEPH S. PODOLSKI;

    申请日2013-04-02

  • 分类号A61K31/573;C07J5;C07J7;

  • 国家 US

  • 入库时间 2022-08-21 16:02:55

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