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Diagnosing and managing venous thromboembolism and intracardiac thrombi using a provoked D-dimer test
Diagnosing and managing venous thromboembolism and intracardiac thrombi using a provoked D-dimer test
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机译:使用诱发性D-二聚体测试诊断和管理静脉血栓栓塞和心内血栓形成
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摘要
The present invention provides methods for diagnosing a venous thromboembolism or intracardiac thrombi in an individual in need of such treatment. A representative method of the present invention comprises the steps of: obtaining a plasma sample from said individual; determining the baseline level of D-dimer in said sample; contacting said sample with a compound that catalyzes the conversion of plasminogen into plasmin; and measuring the level of D-dimer is said sample after administering or contacting said sample with a compound that catalyzes the conversion of plasminogen into plasmin, wherein a significantly greater concentration of D-dimer after contact with a compound that catalyzes the conversion of plasminogen into plasmin than prior to contact with a compound that catalyzes the conversion of plasminogen into plasmin indicates that said individual has pulmonary embolism or venous thromboembolism.
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