embedded image wherein A, B and R1 to R7 are as described below, or to pharmaceutically acceptable salts thereof. These compounds are BACE1 and/or BACE2 inhibitors and can be used as medicaments for the therapeutic and/or prophylactic treatment of diseases such as Alzheimer's disease, diabetes, particularly type 2 diabetes, and other metabolic disorders."/> 2,5,6,7-tetrahydro-1,4oxazepin-3-ylamine or 2,3,6,7-tetrahydro-1,4oxazepin-5-ylamine compounds
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2,5,6,7-tetrahydro-1,4oxazepin-3-ylamine or 2,3,6,7-tetrahydro-1,4oxazepin-5-ylamine compounds

机译:2,5,6,7-四氢-[1,4]草氮杂-3-基胺或2,3,6,7-四氢-[1,4]草氮杂-5-基胺化合物

摘要

This invention relates to compounds of the formula; embedded image wherein A, B and R1 to R7 are as described below, or to pharmaceutically acceptable salts thereof. These compounds are BACE1 and/or BACE2 inhibitors and can be used as medicaments for the therapeutic and/or prophylactic treatment of diseases such as Alzheimer's disease, diabetes, particularly type 2 diabetes, and other metabolic disorders.
机译:本发明涉及下式的化合物: “嵌入式图像” 其中A,B和R 1 至R 7 如下所述,或其药学上可接受的盐。这些化合物是BACE1和/或BACE2抑制剂,并且可用作用于诸如阿尔茨海默氏病,糖尿病,特别是2型糖尿病和其他代谢性疾病的疾病的治疗和/或预防性治疗的药物。

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