HIGH-EFFICIENCY SEPARATION AND MANIPULATION OF PARTICLES AND CELLS IN MICROFLUIDIC DEVICE USING SURFACE ACOUSTIC WAVES AT AN OBLIQUE ANGLE

摘要

An apparatus for manipulating particles within a fluid sample includes a substrate having a substrate surface. A surface acoustic wave (SAW) generator generates a SAW within a SAW region of the substrate surface. The SAW has an SAW direction aligned with a pressure node. A channel is configured to receive the fluid sample and the fluid sample has a flow direction which is at an oblique angle to the SAW direction.