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Host cells and methods of producing disulfide bond containing proteins
Host cells and methods of producing disulfide bond containing proteins
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机译:宿主细胞和产生含有二硫键的蛋白质的方法
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摘要
The invention provides for genetically modified Bacillus host cells having decreased cytoplasmic reductase activity, such as decreased TrxA activity, and a nucleic acid encoding a heterologous Staphylococcal oxidase. The invention also provides for methods of producing di-sulfide bond containing proteins using the host cells of the invention and methods of improving protein folding using the host cell of the invention.
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