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Closed loop flow control of a HPLC constant flow pump to enable low-flow operation
Closed loop flow control of a HPLC constant flow pump to enable low-flow operation
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机译:HPLC恒流泵的闭环流量控制,可实现低流量运行
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摘要
A method and apparatus for monitoring and controlling nano-scale flow rate of fluid in the operating flow path of a HPLC system provide fluid flow without relying on complex calibration routines to compensate for solvent composition gradients typically used in HPLC. The apparatus and method are used to correct the flow output of a typical, analytical-scale (0.1-5 mL/min) HPLC pump to enable accurate and precise flow delivery at capillary (0.1 mL/min) and nano-scale (1 μL/min) HPLC flow rates.
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机译:一种用于监测和控制HPLC系统的工作流径中的纳米级流体流速的方法和设备,无需依靠复杂的校准程序来补偿通常用于HPLC的溶剂组成梯度,即可提供流体流。该设备和方法用于校正典型分析级(0.1-5 mL / min)HPLC泵的流量输出,从而能够在毛细管(<0.1 mL / min)和纳米级(< 1μL/ min)HPLC流速。
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