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Method for inhibiting the formation of SET1 family core complexes
Method for inhibiting the formation of SET1 family core complexes
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机译:抑制SET1家族核心复合物形成的方法
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摘要
Disclosed in this specification is a method for inhibiting the formation of vertebrate SET1 family core complexes. A guanidinium-containing molecule is used to competitively inhibit the binding of the N-SET region of a SET1 protein to WDR5, thus inhibiting the formation of the SET1 family core complex. The guanidinium-containing molecule may be, for example, an arginine-containing peptide.
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