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Control Agent of ectoparasites of animals and method to prevent or treat infections caused by parasites in animals by the use of the control Agent

机译:动物体外寄生虫的防治剂及通过使用该防治剂预防或治疗动物寄生虫引起的感染的方法

摘要

Claim 1: exoparasite control agents, including n-pyridine-pyridan compounds, diene monooxide or salts of these compounds, wherein n-pyridine-pyridan compounds are expressed in formula (1),characterized in that R1 is a halogen atom, a C1-4 haloalkyl group, a cyano group, a nitro group or a C1-4 alkoxycarbonyl group; R2, R3, R4, R5, R6, R7, R8 and R9 are each a hydrogen atom or a C1-4 alkyl group; each pair of R2 and R8, and R4 and R6, can join to form a C1-4 alkylene group; R10 is a hydrogen atom; a C1-20 alkyl group; a C3-8 cycloalkyl group; a C2-6 alkenyl group; a C2-6 alkynyl group; a C1-6 haloalkyl group; a C2-6 haloalkenyl group; a C1-6 alkylcarbonyl group; a C1-6 alkoxycarbonyl group; a benzoyl group optionally substituted on the phenyl ring with one to five halogen atoms;An optional phenyl compound is replaced by one or more substitutes in the cyclic phenyl, each of which is independently selected from the group of halogen, C1-4 tar and C1-4 halide; an optional non periodic substitute is replaced in the heterocyclic ring with one or more substitutes, Each substance is selected independently from halogen, C1-4 tar, C1-4 halo tar and alternative aperiodic groups; or from C1-4 tar groups replaced by one or more alternatives.Each of them is selected independently from the group C3-8 of cyclododecane, which is selectively replaced by halogen, cyanogen, nitrogen, thyroid, oxygen C1-6, halogen C1-4, benzepam, phenyl con (R12) (R13).phenyl optionally substituted on the phenyl ring with one or more halogen atoms, and heterocyclic groups optionally substituted on the heterocyclic ring with one or more C1-4 alkyl groups; wherein R12 and R13 are each a C1-4 alkyl group; or R12 and R13 can join to form a C2-7 alkylene group; R11 is a halogen atom; a C1-6 alkyl group; a C1-4 haloalkyl group; a C1-4 hydroxyalkyl group; a C1-4 alkoxycarbonyl group; a C1-4 alkylcarbonyl group; a mono or di (C1-4alkyl) aminocarbonyl group; a nitro group; a cyano group; a formyl group; -C (R14) = NO (R15);a phenyl group optionally substituted on the phenyl ring with one or more substituents, each independently selected from the group consisting of halogen, C 1-6 alkyl, C 1-4 haloalkyl, C 1-6 alkoxy, C 1-4 haloalkoxy, C1-4alkylthio, cyano and nitro; or a heterocyclic group optionally substituted on the heterocyclic ring with one or more substituents, each independently selected from the group consisting of halogen, C1-4 alkyl, and C1-4 haloalkyl; wherein R14 is a hydrogen atom or a C1-4 alkyl group, and R15 is a hydrogen atom, a C1-4 alkyl group or a benzyl group; X is an oxygen atom,1. O-SO2 sulfur atom;M is an integer between 1 and 4; if M is an integer between 2 or more, the number of R1 represented by M may be equal or different; n is an integer between 1 or 2; if n is 2, Two R11 may be the same or different requirements6: methods of prevention or treatment of parasite infection in animals, including the above-mentioned ectoparasite control of animals in accordance with any one of the requirements 1 to 5.
机译:权利要求1:外寄生虫控制剂,包括n-吡啶-吡啶化合物,二烯一氧化物或这些化合物的盐,其中n-吡啶-吡啶化合物在式(1)中表示,其特征在于R1是卤素原子,C1- 4个卤代烷基,氰基,硝基或C1-4烷氧基羰基; R 2,R 3,R 4,R 5,R 6,R 7,R 8和R 9各自为氢原子或碳数1〜4的烷基。 R2和R8以及R4和R6中的每对可以连接形成C1-4亚烷基。 R10是氢原子; C1-20烷基; C3-8环烷基; C2-6链烯基; C2-6炔基; C1-6卤代烷基; C2-6卤代烯基; C 1-6烷基羰基; C 1-6烷氧羰基;在苯环上任选被一个至五个卤素原子取代的苯甲酰基;任选的苯基化合物被环状苯基中的一个或多个取代基取代,每个取代基独立地选自卤素,C1-4 tar和C1 -4卤化物;杂环中的一个任选的非周期性取代基被一个或多个取代基取代。每种物质独立地选自卤素,C 1-4焦油,C 1-4卤代焦油和非周期性取代基团;或选自被一个或多个取代基取代的C1-4焦油基团。它们各自独立地选自环十二烷的C3-8基团,其被卤素,氰,氮,甲状腺,氧C1-6,卤素C1-选择性取代4,苯甲epa,苯环(R12)(R13)。苯环上任选被一个或多个卤素原子取代的苯基,以及杂环上任选被一个或多个C1-4烷基取代的杂环基;其中R12和R13各自为C1-4烷基; R12和R13可以结合形成C2-7亚烷基。 R11是卤素原子; C 1-6烷基; C1-4卤代烷基; C1-4羟烷基; C1-4烷氧羰基; C1-4烷基羰基;单或二(C 1-4烷基)氨基羰基;硝基;氰基;甲酰基; -C(R14)= NO(R15);任选地在苯环上被一个或多个取代基取代的苯基,所述取代基各自独立地选自卤素,C 1-6烷基,C 1-4卤代烷基,C 1 -6烷氧基,C 1-4卤代烷氧基,C1-4烷硫基,氰基和硝基;或在杂环上任选地被一个或多个取代基取代的杂环基,所述取代基各自独立地选自卤素,C 1-4烷基和C 1-4卤代烷基;其中R14为氢原子或C1-4烷基,R15为氢原子,C1-4烷基或苄基; X是一个氧原子,1。 O-SO 2硫原子; M为1-4之间的整数;如果M是2以上的整数,则由M表示的R1的数目可以相等或不同。 n是1或2之间的整数;如果n为2,则两个R11可能相同或不同.6:预防或治疗动物体内寄生虫感染的方法,包括上述根据要求1至5中任一项对动物进行体外寄生虫防治。

著录项

  • 公开/公告号AR087300A1

    专利类型

  • 公开/公告日2014-03-12

    原文格式PDF

  • 申请/专利权人 OTSUKA AGRITECHNO CO. LTD.;

    申请/专利号AR2012P102683

  • 发明设计人 ENDO YASUHIRO;SHIRAI YUICHI;

    申请日2012-07-25

  • 分类号A61K31/4545;A61P33/14;

  • 国家 AR

  • 入库时间 2022-08-21 15:58:52

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