Polyethylene glycol conjugated factor VIII Group through a Connector; a Pharmaceutical composition comprising Said polyethylene glycol conjugated; use of the composition for treating a disease or trauma of Blood coagulation.

摘要

The present invention provides a biocompatible polymer conjugated to FVIII via one or more cysteine residues, suitably via a linker across a reduced disulphide bond in FVIII, and pharmaceutical compositions comprising such conjugated forms of FVIII.