Isolated Antibody or Antigen binding fragment thereof which specifically binds to human CD48 and blocks the interaction between a Human and a receiver of CD48 CD48; Pharmaceutical composition containing same and its use.

摘要

The present invention provides antibodies that bind to CD48 and methods of using same. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to human CD48. In certain embodiments, the antibodies of the present invention block the binding of CD48 to one or more CD48 receptor. The antibodies of the invention are useful, inter alia, for the treatment of diseases and disorders associated with one or more CD48 biological activities, including the treatment of allergic conditions and other inflammatory conditions.