Capsule for oral administration comprising n Tert Butyl (3 - 5 - methyl - 2 - ((4 - (2) - pyrrolidin-3-yl - 1 - iletoxi) phenyl amino} pyrimidin-4-yl) amino benzenesulfonamide, microcrystalline Cellulose and sodium Stearyl fumarate; Unit dosage form; method to treat myelofibrosis; method of Preparation On; and article Preparation.

摘要

Provided herein are compositions and methods for treating myelofibrosis in a subject. The methods comprise administering to the subject an effective amount of compound which is which is N-tert-butyl-3-[(5-methyl-2-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}pyrimidin-4-yl)amino]benzenesulfonamide or a pharmaceutical salt thereof or a hydrate thereof.