Compounds derived from morphine, ipiode Peripheral Receptor Antagonists, Pharmaceutical composition for oral use; formulation; and reduce the side effects of the opioid Therapy (Div. Sun. 905 - 08).

摘要

The present invention provides a compound of formula I: wherein R 1 , R 2 , R 2' and X - are as defined and described herein, and compositions thereof, useful as peripheral mu opioid receptor antagonists.