Di-n-octyltin 9 - 4 - (2 - 3 - Chloro - fluoro - phenylamino) - 7 - methoxy - il - 6 quinazolin oxy - 1 - methyl - 1.4 - Grabarsky, IT's The Wrong Guy spiro 5.5 - 5 - undecan Ona intermediaries; Crystal form; composite; Preparation procedure; Composition and Pharmaceutical Combination; and their use to treat infectious diseases or allergic L As Airways.

摘要

The present invention relates to a compound of formula (I), which has valuable pharmacological properties, particularly an inhibiting effect on signal transduction mediated by tyrosine kinases, processes for stereoselectively preparing these compounds, particularly pharmaceutical formulations suitable for inhalation and their use for the treatment of diseases, particularly tumoral diseases, benign prostatic hyperplasia and diseases of the lungs and airways.