Derivatives (pyridine-4-IL) -benzene, as NACHR Alpha-7 modulator for Western Sahara; pharmacological synthesis; preparation of pharmacological synthesis process; used in the treatment of Alzheimer's disease, anxiety disorder, schizophrenia, Parkinson's disease.

摘要

The present invention relates to (pyridin-4-yl)benzylamides derivatives and pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy. The invention particularly relates to positive allosteric modulators of nicotinic acetylcholine receptors, such positive allosteric modulators having the capability to increase the efficacy of nicotinic receptor agonists.