首页> 外国专利> A monomer composed of 6-((7s) -7-hydroxy-6,7-dihydro-5h-pirrolo 1,2-c imidazol-7-il-N-methyl-2-naftamida, D-Manitol and alkaline metal salts selected from magnesium and calcium silicate; and a stabilizer of the compound for the prevention and/or silicate L Tumor treatment.

A monomer composed of 6-((7s) -7-hydroxy-6,7-dihydro-5h-pirrolo 1,2-c imidazol-7-il-N-methyl-2-naftamida, D-Manitol and alkaline metal salts selected from magnesium and calcium silicate; and a stabilizer of the compound for the prevention and/or silicate L Tumor treatment.

机译:由6-((7s)-7-羟基-6,7-二氢-5h-吡咯并[1,2-c]咪唑-7-il] -N-甲基-2-萘甲酰胺,D-甘露醇和选自硅酸镁和硅酸钙的碱金属盐;以及用于预防和/或硅酸盐L肿瘤治疗的化合物的稳定剂。

摘要

The present invention provides a solid preparation wherein variation in weight is suppressed, a solid preparation wherein the active ingredient is stabilized, and a stabilization method thereof. A solid preparation containing (1) an active ingredient, (2) D-mannitol and (3) an alkaline earth metal salt selected from magnesium aluminometasilicate and calcium silicate. A method of stabilizing the. active ingredient, including adding an alkaline earth metal salt selected from magnesium aluminometasilicate and calcium silicate.
机译:本发明提供了抑制重量变化的固体制剂,使活性成分稳定的固体制剂及其稳定化方法。包含(1)活性成分,(2)D-甘露糖醇和(3)选自铝硅酸镁镁和硅酸钙的碱土金属盐的固体制剂。一种稳定的方法。活性成分,包括添加选自铝硅酸镁和硅酸钙的碱土金属盐。

著录项

  • 公开/公告号CL2013002579A1

    专利类型

  • 公开/公告日2014-01-24

    原文格式PDF

  • 申请/专利权人 TAKEDA PHARMACEUTICAL COMPANY LIMITED;

    申请/专利号CL20130002579

  • 发明设计人 MISAKI MASAFUMI;HOSHINA WATARU;

    申请日2013-09-09

  • 分类号A61K31/047;A61K31/4188;A61K33/06;A61K33/12;A61K9/20;A61P35/00;

  • 国家 CL

  • 入库时间 2022-08-21 15:58:29

相似文献

  • 专利
  • 外文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号