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Compound of Ergolin from the opposite side of the 5-HT1D receiver; used to treat migrants.
Compound of Ergolin from the opposite side of the 5-HT1D receiver; used to treat migrants.
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机译:从5-HT1D接收器的另一侧来的Ergolin化合物;用来对待移民
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摘要
Provided herein are novel fluoroergoline derivatives and compositions thereof. In other embodiments, provided herein are methods of treatment, prevention, or amelioration of a variety of medical disorders such as, for example, migraine using the compounds and compositions disclosed herein. In still other embodiments, provided herein are methods of agonizing receptors such as, for example, the 5-HT1D and/or the 5-HT1B receptor, without agonizing the 5-HT2B receptor using the compounds and compositions disclosed herein. In still other embodiments, provided herein are methods of antagonizing or inhibiting activity at receptors such as, for example, the adrenergic alpha2A and/or the alpha2B receptors using the compounds and compositions disclosed herein.
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