Antibiotic compounds of 2 - oxo - 3.5 - oxazolidin dilaurate formula I; Pharmaceutical Composition and use for the Prevention or treatment of a bacterial infection.

摘要

The invention relates to antibacterial compounds of formula I wherein R1a represents H or carboxy and R1b represents H, or R1a and R1b represent together either the group *C(O)NHS# or the group *C(OH)NS# wherein * represents the point of attachment of R1a and # represents the point of attachment of R1b; R2 represents H, (C1-C3)alkyl, hydroxy-(C1-C3)alkyl, benzyl or (C3-C5)cycloalkyl; R3 represents H or halogen; U represents N or CR4; wherein R4 is H or (C1-C3)alkoxy; A represents CH, B represents NH and m represents 1 or 2 and n represents 1 or 2; or A represents N, B is absent, m represents 2 and n represents 2; Y represents CH or N; and Q represents O or S; and salts of such compounds.