- pirrolotriazina benzotienilo derived compounds as inhibitors of protein tyrosine kinase; procedure of preparation of these Compounds, Pharmaceutical composition that comprises; and its use for the treatment and / or the Prevention of Cancer and Tumor disease.

摘要

This invention relates to novel substituted 5-(1-benzothiophen-2-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine derivatives having protein tyrosine kinase inhibitory activities, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for treating proliferative disorders, in particular cancer and tumor diseases.