method of molecular design and synthesis of clinical and preventive medicines

摘要

the invention can be used in medicine and veterinary medicine for the design (and the synthesis of clinical and preventive medicine) effective for the treatment of the unc u043eu043bu043eu0433u0438u0447u0435u0441u043au0438u0445, virus diseases of humans and animals, and for the design of new drugs.a new way to design and synthesis of clinical and preventive medicines, which are u0431u0438u043eu043fu043eu043bu0438u043cu0435u0440 target (protein, dna, rna, or their mixture) as well as u043bu0438u0433u0430u043du0434u0430 uses the same u0431u0438u043eu043fu043eu043bu0438u043cu0435u0440 target, but sliced at u043eu043bu0438u0433u043eu043cu0435u0440u043du044bu0435 fragments (u043du0443u043au043bu0435u0430u0437u0430u043cu0438, synthetic u043du0443u043au043bu0435u0430u0437u0430u043cu0438 and u043fu0440u043eu0442u0435u0430u0437u0430u043cu0438)to modify by changing the charge on the opposite (u0430u0446u0438u043bu0438u0440u043eu0432u0430u043du0438u0435u043c u0430u043du0433u0438u0434u0440u0438u0434u0430u043cu0438 u0434u0438u043au0430u0440u0431u043eu043du043eu0432u044bu0445 acids or u0430u043bu043au0438u043bu0438u0440u043eu0432u0430u043du0438u0435u043c u0433u0430u043bu043eu0433u0435u043du043au0430u0440u0431u043eu043du043eu0432u044bu043cu0438 acids), and as u043bu0438u0433u0430u043du0434u0430 uses the same u0431u0438u043eu043fu043eu043bu0438u043cu0435u0440 target, which is modified by partial replacement of charge molecules in opposite sign with education u0441u0443u043fu0440u0430u043cu043eu043bu0435u043au0443u043bu044fu0440u043du044bu0445 ensembles of biopolymers.we used u0441u0443u043fu0440u0430u043cu043eu043bu0435u043au0443u043bu044fu0440u043du044bu0439 ensemble of u043eu043bu0438u0433u043eu043cu0435u0440u043eu0432 hydrolysis products with modified biopolymers, but opposite charges on the molecule, as well as the hour u0442u0438u0447u043du043e modified shock whole biopolymers.the application of the method allows to reduce significantly the cost of design and synthesis of new drugs, to extend the range of the existing b u0435u043bu043au043eu0432u044bu0445 genetic engineering medicines, to create new classes of dynamic u0441u0430u043cu043eu0430u0434u0430u043fu0442u0438u0440u0443u044eu0449u0438u0445u0441u044f body and targets of drug and u043fu0440u043eu0444u0438u043bu0430u043au0442u0438u0447u0435u0441u043au0438 x medications.