CLATRIC COMPLEXES β-CYCLODEXTRIN WITH 1 - {6-BROM-1-OPH-4-METHOXI-2-FENYL-TOMETHYL-1-AP-4-BENIL-3-FENILTIOMETHYL-1-N-INDYL-3-PHENYLETIOMETHYL-1-N-INDOL-3-BIO-2-FENYLETIOMETHYL-1-N-INDYL-3-BETCH APPLICATION

摘要

The invention relates to a new β-cyclodextrin clathrate complex with 1 - {[6-bromo-1-methyl-5-methoxy-2-phenylthiomethyl-1-H-indole-3-yl] carbonyl} -4-benzylpiperazine of formula (1) when the molar ratio of the derivatives of 1 - {[6-bromo-1-methyl-5-methoxy-2-phenylthiomethyl-1-H-indole-3-yl] carbonyl} -4-benzylpiperazine: β-cyclodextrin from 1: 1 to 1 :ten. The invention also describes solid-phase and liquid-phase methods for the preparation and use of said clathrate complex.