biological microchip for the quantitative determination of immunoglobulin e and g levels in biological fluids, method of analysis using it and a set of reagents, including

摘要

the present invention relates to biochemistry and medicine, in particular to analytical biochemistry and u0438u043cu043cu0443u043du043eu0445u0438u043cu0438u0447u0435u0441u043au043eu043cu0443 analysis and the biological of on u0441u043du043eu0432u0435 u0433u0438u0434u0440u043eu0433u0435u043bu0435u0439 for simultaneous quantification of allergen specific and total immunoglobulin e levels and / or g in biological fluids.biological microchip contains elements with different u0438u043cu043cu043eu0431u0438u043bu0438u0437u043eu0432u0430u043du043du044bu043cu0438 shops, can cause human allergic reactions involving u0438u043cu043cu0443u043du043eu0433u043bu043e u0431u0443u043bu0438u043du043eu0432 classes e and g, as well as, if necessary, further elements with u0438u043cu043cu043eu0431u0438u043bu0438u0437u043eu0432u0430u043du043du044bu043cu0438 antibodies against human immunoglobulin class e and / or g and u044du043bu0435u043cu0435 u043du0442u044b with u0438u043cu043cu043eu0431u0438u043bu0438u0437u043eu0432u0430u043du043du044bu043cu0438 u0438u043cu043cu0443u043du043eu0433u043bu043eu0431u0443u043bu0438u043du0430u043cu0438 rights classes e and / or g.the invention also relates to a method for the simultaneous quantitative analysis of immunoglobulin classes e and g in the biological u043cu0438u043au0440u043eu0447u0438u043fu0435 and recruitment of u0440u0435u0430u0433 u0435u043du0442u043eu0432 to undertake quantitative analysis, including the biological microchip.the invention also provides a calibration dependencies to determine the concentrations of the various immunoglobulin directly on the u043cu0438u043au0440u043eu0447 tabebuia impetiginosa, using elements of the microchip containing u0438u043cu043cu043eu0431u0438u043bu0438u0437u043eu0432u0430u043du043du044bu0435 immunoglobulins in different concentrations.the invention may find use in the diagnosis and monitoring of treatment and different type, involving immunoglobulin classes e and g.