monoclonal antibodies specific for beta u0430u043cu0438u043bu043eu0438u0434u0430 x 37, and the way of application

摘要

the present invention provides a monoclonal antibody specific u0440u0430u0441u043fu043eu0437u043du0430u044eu0449u0438u0435 shorter peptides u0430u03b2 obtained after splitting arr - protein, u043eu043fu043eu0441u0440u0435 u0434u0443u0435u043cu043eu0433u043e gamma u0441u0435u043au0440u0435u0442u0430u0437u043eu0439). fragments of Au03b21 Au03b23 37, 37, Au03b23p Au03b211 37, 37, and Au03b211p - 37 u043fu0435u043fu0442u0438u0434u0430 u0430u03b2 and other such fragments ending 37 u0430u043cu0438u043du043eu043au0438u0441u043bu043eu0442u043eu0439 arr, further in this document to refer to s u043fu0435u043fu0442u0438u0434u0430u043cu0438 u0430u03b2u0445 - 37.further provided u0433u0438u0431u0440u0438u0434u043eu043cu043du044bu0435 cells producing monoclonal antibodies, as well as ways of obtaining antibodies and u0433u0438u0431u0440u0438u0434u043eu043cu043du044bu0445 cells; and u0438u043cu043cu0443u043du043eu043bu043eu0433u0438u0447u0435u0441 the cue analysis u043fu0435u043fu0442u0438u0434u0430 u0430u03b2u0445 - 37 through a competitive method or a method using an antibody according to the present invention; and methods of measuring the levels of peptides u0430u03b2u0445 - 37 in a sample such as a biological sample.