首页> 外国专利> Crystalline hydrated form of bis (e) - 7 - 4 - (4 - fluorophenyl) - 6 - isopropyl - 2 - methyl (methylsulphonyl) amino pyrimidin - 5 - yl (3r,5s) - 3,5 - dihydroxyhept - 6 - enoic acid calcium salt, process for its preparation, pharmaceutical compositions comprising the same and use thereof in the manufacture of a medicament for medical treatment

Crystalline hydrated form of bis (e) - 7 - 4 - (4 - fluorophenyl) - 6 - isopropyl - 2 - methyl (methylsulphonyl) amino pyrimidin - 5 - yl (3r,5s) - 3,5 - dihydroxyhept - 6 - enoic acid calcium salt, process for its preparation, pharmaceutical compositions comprising the same and use thereof in the manufacture of a medicament for medical treatment

机译:双[(e)-7-[4-(4-氟苯基)-6-异丙基-2-[甲基(甲基磺酰基)氨基]嘧啶-5-yl](3r,5s)-3,5-的晶体水合形式[二羟基庚基-6-烯酸]钙盐,其制备方法,包含该盐的药物组合物及其在制备用于治疗的药物中的用途

摘要

Two polymorphic forms of bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid]calcium salt, processes for making them and their use as HMG Co-A reductase inhibitors are described.
机译:双[(E)-7- [4-(4-氟苯基)-6-异丙基-2- [甲基(甲基磺酰基)氨基]嘧啶-5-基](3R,5S)-3,5-的两种多晶型形式描述了二羟基庚基-6-烯酸]钙盐,其制备方法及其作为HMG Co-A还原酶抑制剂的用途。

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