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Intraocular drug delivery systems including microspheres comprising a therapeutic agent and polylactic acid and use thereof in the preparation of medicaments
Intraocular drug delivery systems including microspheres comprising a therapeutic agent and polylactic acid and use thereof in the preparation of medicaments
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机译:眼内药物输送系统,包括包含治疗剂和聚乳酸的微球,及其在药物制备中的用途
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摘要
Biodegradable implants sized and suitable for implantation in an ocular region or site and methods for treating ocular conditions. The implants provide an extended release of an active agent at a therapeutically effective amount for a period of time between 10 days and one year or longer. The biocompatible, injectable intraocular drug delivery system comprises a plurality of microspheres in aqueous medium and an alpha Z adrenergic agonist such as brimonidine and biodegradable polyactic acid (PLA) polymers.
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