'FORMULATION amp; EVALUATION OF GASTRORETENTIVE FLOATING MICROSPHERES OF CEFUROXIME AXETIL'

摘要

The present invention relates to floating microspheres of Cefuroxime axetil. The formulation provides an extended retention in the upper GIT(Gastro Intestinal Tract), which results in enhanced absorption and thereby improved bioavailability of the drug. The microspheres of Cefuroxime axetil are prepared using Hydroxy propyl methyl cellulose (K4M) and ethyl cellulose by non-aqueous solvent evaporation method.