IDENTIFICATION AND RESIDUAL DETECTION OF IVABRADINE HYDROCHLORIDE A- CRYSTALLINE FORM IN D- CRYSTALLINE FORM AND DD- CRYSTALLINE FORM OF IVABRADINE HYDROCHLORIDE DRUG SUBSTANCE AND DRUG PRODUCT BY SOLID STATE NMR:

摘要

The present invention relates to the technique in which the residual level of a– crystalline form in d- crystalline form and dd- crystalline form of Ivabradine hydrochloride drug substance or drug product of formula (I) identified by Solid State NMR. Formula (I)