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METHOD FOR ANALYZING MUCIN 1 USING PROBE CAPABLE OF BINDING TO 3´- SULFONATED CORE 1 CARBOHYDRATE CHAIN, AND METHOD FOR DETECTING OR MONITORING BREAST CANCER
METHOD FOR ANALYZING MUCIN 1 USING PROBE CAPABLE OF BINDING TO 3´- SULFONATED CORE 1 CARBOHYDRATE CHAIN, AND METHOD FOR DETECTING OR MONITORING BREAST CANCER
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机译:使用能够与3´-磺化核心1碳酸盐链结合的探针分析粘蛋白1的方法以及检测或监测乳腺癌的方法
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摘要
The purpose of the present invention is to provide a method for detecting even mucin 1 derived from breast cancer, which cannot be detected by a CA15-3 measurement method. The purpose can be achieved by a method for analyzing mucin 1 having a Sulfo-3Galß1-3GalNAc- R carbohydrate chain, characterized by comprising: a step of bringing a 3´-sulfonated core 1 carbohydrate chain binding probe capable of binding to the Sulfo-3Galß1-3GalNAc-R carbohydrate chain into contact with a sample to be tested; a step of bringing a 3´ sulfonated core 1 carbohydrate chain mucin 1 peptide binding probe capable of binding to mucin 1 having the Sulfo-3Galß1-3GalNAc-R carbohydrate chain or a mucin 1 binding probe capable of binding to mucin 1 into contact with the sample; and a step of detecting a bonded product of mucin 1 having the Sulfo 3Galß1-3GalNAc-R carbohydrate chain and the probes.
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