ECTOPARASITICIDAL SPOT-ON FORMULATIONS COMPRISING FIPRONIL AND AMITRAZ

摘要

The present invention provides a parasiticidal spot-on formulation for the treatment or prevention of parasite infestations in non-human mammals or birds comprising an ectoparasiticidal combination comprising of fipronil and amitraz; a pharmaceutical or veterinary acceptable liquid carrier vehicle for applying the formulation to a localized region on an animal comprising a solvent and optionally a cosolvent and optionally, a crystallization inhibitor. The inventive formula remains effective up to three months from the first application. Moreover, the inventive formulations prevent tick attachment to the animal, thereby providing protection against tick borne diseases. The ectoparasites which may be controlled, treated or prevented by the present invention includes ticks, fleas, mites, mange, lice, mosquitoes, flies and cattle grubs.