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Method for predicting the course of II and III stage malignant melanoma

机译:Ⅱ,Ⅲ期恶性黑色素瘤病程的预测方法

摘要

The invention relates to medicine, particularly to oncology and can be used for predicting the course of II and III stage malignant melanoma.According to the invention, the claimed method involves the clinical and paraclinical examination, where are determined the following parameters: clarification of the stage of disease (ST), presence of ulcer formation (U), tumor cell type (TCT), Clark's level of invasion (NI), tumor thickness under Breslow (GT); applied method of treatment (MT) and sex of the patient (SP), then it is calculated the discriminant function (F) by the formula:F= -6,345 + 1,386 × ST + 4,768 × MT - 2,596 × SP - 3,384 × U + 0,806 × TCT + 1,780 × NI - 1,136 × GT.In the case where F 0 is predicted a favorable course of malignant melanoma, and when F 0 - an unfavorable course.
机译:本发明涉及医学,特别是涉及肿瘤学,并且可以用于预测II和III期恶性黑色素瘤的病程。根据本发明,要求保护的方法涉及临床和临床旁检查,其中确定以下参数:疾病的阶段(ST),溃疡形成的存在(U),肿瘤细胞类型(TCT),克拉克的侵袭水平(NI),Breslow下的肿瘤厚度(GT);应用治疗方法(MT)和患者性别(SP),然后通过以下公式计算判别函数(F):F = -6,345 + 1,386×ST + 4,768×MT-2,596×SP-3,384×U + 0,806×TCT + 1,780×NI-1,136×GT。在预测F <0的情况下,恶性黑色素瘤的病程良好,而当F> 0时,则为不良病程。

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