GEL OR CREAM OF TOPICAL APPLICATION WITH BOTULINUM NEUROTOXIN ENCAPSULATED IN LIPOSOMAL NANOPARTICLES FOR TREATING HYPERHIDROSIS.

摘要

The present invention refers to a stable formulation of cream or gel of botulinum neurotoxin type A coupled to liposomal nanoparticles of third generation of topical application for treating hyperhidrosis. The formulation contains a thickening agent, an emulsifying agent and a hydrating agent in a pH similar to the human skin. The use of this formulation of topical application is useful for reducing the dose of toxin applied by session, avoiding pain associated to the injections and obtaining a clinical effect of inhibition of sweating.