PHARMACEUTICAL COMPOSITION WITH FLOATING UNITS OF MODIFIED RELEASE AND UNITS OF IMMEDIATE OR MODIFIED RELEASE.

摘要

The present invention refers to a composition comprising a system of biphasic delivery that includes: a) one or more floating units of modified release containing i) at least a lipase inhibiting agent or the pharmaceutically acceptable salts thereof and/or derivatives and/or prodrugs and/or polymorphes and/or amorphes and/or ii) one or more hydrophilic polymers, and or iii) one or more silicon salts and/or iv) one or more pharmaceutically acceptable excipients; b) one or more units of immediate release containing i) at least a natural quaternary amine selected from Carnitine or L-carnitine and derivatives of acyl-carnitine, the pharmaceutically acceptable salts thereof and/or derivatives and/or prodrugs and/or polymorphes and/or amorphes, and/or ii) one or more pharmaceutically acceptable excipients thereof; and in an optional manner, c) one or more units of immediate and/or modified release containing i)one or more liposoluble vitamins and/or the pharmaceutically acceptable salts the reof and/or derivatives and/or prodrugs and/or polymorphes and/or amorphes; and/or ii) one or more pharmaceutically acceptable excipients.