chiral poliamfolity acid derivatives dimetylofosfinowego, polialkilenopoliamin and valine and their manufacture

摘要

the invention relates to chiralnych poliamfolitu00f3w acid derivatives dimetylofosfinowego, polialkilenopoliamin and valine, which are intended for use as enancjoselektory and diastereoselektory, and kompleksony to manufacture chiralnych catalysts homogennych and heterogennych presented in zorem general and.process for the production of chiralnych poliamfolitu00f3w acid derivatives dimetylofosfinowego, polialkilenopoliamin and valine of the general formula i, in which a means of structure of dimetylofosfinowego, x is the number of such fragments in poliamfolicie, while b is the fragment structure polia lkilenopoliaminy, in which n and p can be same or different and denote integers from 2 to 12.however, q is the number of structures aminopolialkenowych and ranges from 2 to 6, and y means the number of fragments poliaminopolialkenowych in polymer, and c is a structure of valine, and means the number of such fragments in poliamfolicie, characterized by that,in the first stage, one part acid molar fosfinowego undergo reaction with at least one part of the molar formaldehyde contained in substance selected from the group of formaldehyde, trioxane, paraform, and at least two parts molowymi groups - nh -, which consists of the sum of - nh groups - from polialkilenopoliaminy selected from a group of bis (hexamethylene) triaminu0119, dietylenotriaminu0119,n - (3-aminopropyl) - 1,3 - diaminopropane, n - (2-aminoethyl) - 1,3 - diaminopropane - n, n '- bis (3-aminopropyl) ethylenediamine, trietylenotetraminu0119, tetraerylenopentaminu0119, pentaetylenoheksaminu0119, diaminoetan 1,2 -, 1,3 - diaminopropane, 1,4-diaminobutane, 1,5 - diaminopentan, 1,6 - diaminoheksan, 2 - methyl - 1.5 - diaminop entan and 1,2 1,3-diaminocyclohexane, and groups of - nh - from valine,a reaction is at a temperature of 273 - 373k, in water, in the presence of an activator in the form of free acid bronsteda until przereagowania substrates and formation of mixtures of fatty aminometylofosfinowych, derivatives polialkilenopoliamin and valine.in the second stage, which is subjected to at least one part of usieciowaniu formaldehyde molar in the presence of activator in the form of any of bronsteda until przereagowania substrates and formation of chiralnego poliamfolitu containing structural fragments of dimetylofosfinoweg oh, polialkilenopoliaminy and valine, which in the third stage is dosieciowaniu at least 0,5 parts of formaldehyde molar, after which the so obtained chiralny poliamfolit releases of mixtures poreakcyjnej.