首页>
外国专利>
Compositions and methods for inhibiting expression of pro-apoptotic genes
Compositions and methods for inhibiting expression of pro-apoptotic genes
展开▼
机译:抑制促凋亡基因表达的组合物和方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The invention relates to one or more inhibitors, in particular siRNA compounds, which down-regulate the expression of a pro-apoptotic gene selected from the group consisting of TP53; HTRA2; KEAP1; SHC1-SHC, ZNHIT1, LGALS3 and HI95. The invention also relates to a pharmaceutical composition comprising the compound, and a pharmaceutically acceptable carrier. The present invention further provides methods of treating a subject afflicted with a disease or a condition associated with those genes, comprising administering to the subject a pharmaceutical composition in a therapeutically effective dose so as to thereby treat the subject.
展开▼