METHOD FOR DIAGNOSTICS OF DEGREE OF SEVERITY OF TRAUMATIC INJURY AND PREDICTION OF PROBABILITY OF LETHAL OUTCOME

摘要

A method for diagnostics of degree of severity of traumatic injury and prediction of probability of lethal outcome includes evaluation of functional characteristics of patient organism. Additionally during the first day of hospitalization spectrophotometric determination of concentration of carbonyl groups of protein in patient’s blood plasma is performed by means of reaction with 2,4-dinitrophenylhydrazine and malonic dialdehyde by means of reaction with thiobarbituric acid, obtained characteristics are divided by concentration of total protein determined by biuretic method. When concentration of malonic dialdehyde is from 0.1023 to 0.1448 µmol/g and of carbonyl groups is from 14.14 to 17.46 µmol/g the degree of traumatic shock is diagnosed as light, with possible level of mortality 20 %, when concentration of malonic dialdehyde is from 0.1023 to 0.1448 µmol/g and concentration of carbonyl groups is from 10.77 to 14.14 µmol/g the degree of traumatic shock is diagnosed as moderate, with possible level of mortality 50 %, when concentration of malonic dialdehyde is above 0.1448 µmol/g or lower than 0.1023 µmol/g and concentration of carbonyl groups is above 17.46 µmol/g or lower than 10.77 µmol/g the degree of traumatic shock is diagnosed as severe, with 100 % probability of mortality.