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METHODS OF CONVERTING A PATIENT'S TREATMENT REGIMEN FROM INTRAVENOUS ADMINISTRATION OF AN OPIOID TO ORAL CO-ADMINISTRATION OF MORPHINE AND OXYCODINE USING A DOSING ALGORITHM TO PROVIDE ANALGESIA
METHODS OF CONVERTING A PATIENT'S TREATMENT REGIMEN FROM INTRAVENOUS ADMINISTRATION OF AN OPIOID TO ORAL CO-ADMINISTRATION OF MORPHINE AND OXYCODINE USING A DOSING ALGORITHM TO PROVIDE ANALGESIA
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机译:使用给药算法将镇静剂从阿片类药物的静脉给药转变为吗啡和羟考定的口服共给药的方法
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摘要
A method of converting a treatment for pain comprising intravenous administration of opioids, to a treatment for pain comprising oral administration of a first dose of an immediate release mgrphine-oxycodone combination in patients in need of analgesia. The method may comprise (1) determining a four-hour average oral morphine equivalents, a one-hour average oral morphine equivalents, or determining a net average hourly inlravenous dose, and (2) orally administering to the patient a first dose of a morphine-oxycodone combination in a 3:2 ratio by weight every four to six hours. Also, a method of treating pain in patients who had been administered opioids intravenously, comprising using a dosing algorithm lo determine the first dose of the immediate release morphine-oxycodone combination.
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