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Method of administration for pharmaceutically active peptides with sustained release of the active substance and procedure for their preparation

机译:具有持续释放活性物质的药物活性肽的给药方法及其制备方法

摘要

Pharmaceutical gel preparation, comprising a mixture of at least one pharmaceutically active ionic peptide compound, with a length of 8 to 12 amino acids, in lyophilized form, in a concentration of 5 to 50 mg of peptide per ml of the total amount of pharmaceutical preparation, and an aqueous solution of an inorganic salt or an acetic acid salt, in a concentration of 0.01% to 0.9% (w / v), where after mixing, the pharmaceutical gel preparation is can be administered immediately or after a residence time of up to about 120 minutes, preferably between about 10 min to about 120 min
机译:药物凝胶制剂,其包含至少一种具有冻干形式的长度为8至12个氨基酸的药物活性离子肽化合物的混合物,每毫升药物制剂总量中的浓度为5至50 mg肽以及浓度为0.01%至0.9%(w / v)的无机盐或乙酸盐的水溶液,其中混合后,可立即或在停留时间超过90分钟后给药至约120分钟,优选约10分钟至约120分钟

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