Process for obtaining diene compounds of trans configuration useful as intermediates for the synthesis of vitamin d analogues and use of a corresponding microreactor (Machine-translation by Google Translate, not legally binding)

摘要

Process for obtaining diene compounds of trans configuration useful as intermediates for the synthesis of vitamin d analogues and use of a corresponding microreactor. Process for obtaining diene compounds of general structure (II), useful as intermediates for the synthesis of vitamin d analogs, ****image**** Where x and y can be the same or different and represent hydrogen, oh or a group or1/or2, where r1 and r2 hydroxyl protecting groups, and r is a chain of 1 to 6 carbon atoms, saturated or unsaturated, and substituted or unsubstituted, by deprotection of compounds of general structure (I), characterized in that the the reaction is carried out in the presence of an amine and continuously in a microreactor.