Using phospholipase A2 secreted in the diagnosis and treatment of malaria

摘要

A method in vitro of an infection by Plasmodium diagnosis in a subject, characterized by comprising the following steps: a) measuring the concentration in the selected serum at least one A2 secreted phospholipase (sPLA2) the group consisting of sPLA2 GIIF, GV and GX, in said subject, in a blood sample, b) comparing the serum concentration of sPLA2 GIIF, GV and / or GX obtained in step a) with the reference concentration in serum sPLA2 GIIF, GV and / or GX in subjects not infected with Plasmodium respectively, wherein a concentration higher than in the serum of GIIF sPLA2, GV and / or GX in said blood sample of said subject compared to the reference concentration in the serum of sPLA2 GIIF, GV and / or GX in subjects not infected with Plasmodium, is indicative that said subject is infected with Plasmodium me.