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molecular prognostic and classification of malignant melanoma based on markers selected from the list consisting of RGS1, NCOA3, SPP1, PHIP

机译:基于选自RGS1,NCOA3,SPP1,PHIP的标志物的恶性黑色素瘤分子预后和分类

摘要

A method of providing a prognosis for melanoma in a subject, the method comprising the steps of: (a) contacting a biological sample from the subject with reagents that specifically bind to selected markers comprising: (i) RGS1 polypeptides, NCOA3 , SPP1, and PHIP, or (ii) nucleic acids encoding the polypeptides, wherein there is at least one reagent binding to each marker; and (b) determining whether each of the selected markers is overexpressed or not in the sample; thereby providing a prognosis for melanoma in the subject.
机译:一种为受试者提供黑色素瘤预后的方法,该方法包括以下步骤:(a)使来自受试者的生物样品与特异性结合所选标记的试剂接触,所述试剂包括:(i)RGS1多肽,NCOA3,SPP1和PHIP,或(ii)编码多肽的核酸,其中至少一种试剂与每种标记结合; (b)确定每个选择的标记在样品中是否过表达;从而提供受试者中黑素瘤的预后。

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